Commercial Strategy & Execution Lead

Company: Legend Biotech
Location: Bridgewater
Posted on: January 14, 2026

Job Description:

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Commercial Strategy & Execution Lead as part of the Commercial team based in Bridgewater, NJ . Role Overview The Commercial Strategy & Execution Lead serves as a strategic thought partner and operational leader, driving execution of high-priority business initiatives and ensuring seamless integration across the Commercial organization. The role will report to SVP, Head of Commercial and will act as an extension of the SVP. The position will oversee strategic planning, 4DX execution, foster cross-functional alignment, and enable efficient operations across Sales, Marketing, Market Access, External Engagement, Commercial Assessment, and Commercial Operations. The ideal candidate brings a proven track record in leadership, strategic execution, project management, and operational excellence, with exceptional communication and collaboration skills. Key Responsibilities Manage and facilitate key leadership meetings, including Commercial Leadership Team sessions, Quarterly Business Reviews, and strategic planning forums. Partner with functional leaders across Sales, Marketing, Market Access, External Engagement, and Operations to drive alignment and execution of Carvykti’s commercial strategy. Ensure integration of commercial performance dashboards (4DX) and monitor organizational progress in collaboration with the PMO; contribute to vision-setting and prioritization of commercial initiatives. Foster a culture of transparency, collaboration, and engagement across the commercial organization. Track and manage SVP-assigned priorities and deliverables, ensuring timely completion and accountability. Identify operational efficiencies and implement solutions to enhance organizational effectiveness. Lead special projects and strategic initiatives requiring cross-functional collaboration and analysis of commercial performance. Interface with corporate functions including Finance, HR, IT, and Legal to ensure seamless integration and support for commercial priorities. Support ad hoc strategic analyses and opportunity assessments to inform commercial decision-making. Drive execution of the 4DX (Four Disciplines of Execution) roadmap, ensuring focus on Wildly Important Goals (WIGs), lead measures, and accountability through regular cadence reviews. Partner with the Commercial Culture Club to design and implement culture-building initiatives that reinforce engagement and high-performance behaviors. The authority to make decisions related to project execution, including timelines, milestones and resource allocation within budget. Requirements Bachelor's degree with 7 years of industry experience and demonstrated leadership in project and/or operational management. Master degree preferred Creative, strategic thinking, operational effectiveness, and strong troubleshooting skills Strong holistic approach to working with groups of high-performance individuals. Able to pull the best from teams while at the same time being able to contribute and help synthesize. High EQ with ability to build trust with stakeholders (e.g., Commercial team, BU President, executive leadership, etc.) Ability to work effectively in a collaborative, fast-paced environment with competing priorities while also making a strong personal impact. Ability to set and follow through goals with a sense of urgency while keeping broader strategic objectives in focus and delivering high standard outcomes. Exceptional interpersonal skills. Excellent planning, prioritization, and organizational skills. Excellent communication skills, verbal, graphical, and written, with a keen sense of how to connect with people and build trust. Effective presentation skills to key stakeholders and key decision makers. Working experience in Commercial organizations and good understanding of external landscape. Li-JK1 Li-Contract Benefits We are committed to creating a workplace where employees can thrive - both professionally and personally. To attract and retain top talent in a highly competitive industry, we offer a best-in-class benefits package that supports well-being, financial stability, and long-term career growth. Our offerings are designed to meet the diverse needs of our team members and their families, ensuring they feel valued and supported every step of the way. Highlights include medical, dental, and vision insurance as well as a 401(k)-retirement plan with company match that vest fully on day one. Equity and stock options are available to employees in eligible roles. We offer eight weeks of paid parental leave after just three months of employment, and a paid time off policy that includes vacation days, personal days, sick time, 11 company holidays, and 3 floating holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs - demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work. Please note: These benefits are offered exclusively to permanent employees. Contract employees are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend may adjust base salary or other discretionary compensation at any time based on individual, team, performance, or market conditions. Legend Biotech maintains a drug-free workplace.

Keywords: Legend Biotech, Freeport , Commercial Strategy & Execution Lead, Accounting, Auditing , Bridgewater, New York